Table 1.

Guidance questions to be considered

Secondary prevention following provoked VTE

Should thrombophilia testing be performed to help determine duration of anticoagulation following provoked VTE?

Secondary prevention following unprovoked VTE

Should thrombophilia testing be performed to help determine duration of anticoagulation following unprovoked VTE?

Primary prevention in relatives of VTE patients

Should family members of patients with VTE or hereditary thrombophilia undergo thrombophilia testing?

Primary prevention in female relatives of VTE patients considering estrogen

Should female relatives of patients with VTE or hereditary thrombophilia who are considering using estrogen-containing medications be tested for thrombophilia?

Primary prevention in female relatives of VTE patients who are contemplating pregnancy

Should female relatives of patients with VTE or hereditary thrombophilia who are contemplating pregnancy be tested for thrombophilia?

Timing of thrombophilia assessment

When thrombophilia testing is performed, at what point in the patient’s care should this be done?