Table 1.

Guidance questions to be considered

What are the major goals of thrombolytic therapy for DVT and PE?

What are the risk stratification criteria for thrombolytic therapy for PE and DVT?

Is systemic thrombolytic therapy recommended for PE and DVT?

When and what types of catheter-directed thrombolysis are recommended for DVT and PE?

How can safety during thrombolytic infusions be optimized?

When should IVC filters be used with thrombolytic therapy?

When should surgical embolectomy be considered?