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. Author manuscript; available in PMC: 2016 Jan 17.
Published in final edited form as: Nat Commun. 2015 Mar 6;6:6393. doi: 10.1038/ncomms7393

Figure 1. The ubiquinone (UQ) biosynthetic pathway.

Figure 1

(a) Schematic overview of the UQ biosynthesis pathway. 4-hydroxybenzoic acid (4-HB) is the aromatic ring precursor of UQ. MCLK1/COQ7 carries out the penultimate biosynthetic step, the hydroxylation of demethoxyubiquinone (DMQ). (b) Chemical structure of 2,4-dehydroxybenzoic acid (2,4-DHB). “n” denotes the number of subunits of the isoprenoid side chain.