Table 1.
No. | Mean age at Dx* | Latency | Histology (%)** | MM location (%)*** | Gender (% M vs. F) | Cancer score | |
---|---|---|---|---|---|---|---|
BAP1-mutant MM cases | 9 | 57.9 ± 10.7 | 44.5 ± 9.9 | 88.9/11.1/0/0 | 44.4/55.6 | 77.8/22.2 | 3.00 ± 1.22 |
WT BAP1 MM cases | 141 | 68.2 ± 10.9 | 50.9 ± 11.2 | 73.8/9.9/13.5/2.8 | 82.3/17.7 | 75.2/24.8 | 2.4 ± 0.95 |
Significance: BAP1-mutant vs. WT BAP1 MM controls | p < 0.01 | NS | NS | p < 0.05 | NS | NS | |
Controls: asbestosis +/− pleural plaques | 153 | 74.6 ± 4.9 | 54.4 ± 3.7 | 92.2/7.8 | |||
Controls: High cancer score without MM | 50 | 72.8 ± 9.8 | 86.0/14.0 | 4.34 ± 1.46 |
For controls, age at time that blood sample was collected.
Epithelioid/biphasic/sarcomatous/unknown
% pleural/% peritoneal
Key: WT, wild-type (normal) BAP1 status; Dx, diagnosis; M, male; F, female