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. Author manuscript; available in PMC: 2017 Feb 1.
Published in final edited form as: J Affect Disord. 2015 Nov 17;191:123–131. doi: 10.1016/j.jad.2015.11.012

Table 2.

Estimates for the Top Five SNPs from the QTL-specific Association Analysis in (a) the Entire Sample and (b) the Multiplex MDD Pedigree for the Continuous Depression Score.

Entire Sample
SNP χ2 p-value β Variance Explained MAF HWE p-value
rs11245316 11.28 0.000783 0.15 0.009 0.213 0.88
rs3884528 9.09 0.002565 -0.11 0.008 0.466 0.18
rs4578341 7.51 0.006127 0.12 0.008 0.219 0.98
rs1123988 7.38 0.00658 0.11 0.007 0.006 0.86
rs859556 7.30 0.00688 -0.58 0.006 0.006 0.96
Multiplex Pedigree
rs7913161 17.84 0.000024 0.69 0.150 0.163 0.38
rs4995180 16.19 0.000057 1.35 0.139 0.025 0.45
rs7906808 15.35 0.000089 1.95 0.133 0.006 0.66
rs7906939 14.28 0.000158 1.52 0.131 0.010 0.69
rs7095366 14.17 0.000167 1.18 0.116 0.021 0.51