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. Author manuscript; available in PMC: 2017 Jan 1.
Published in final edited form as: Microbes Infect. 2015 Sep 8;18(1):21–29. doi: 10.1016/j.micinf.2015.08.015

Fig. 1.

Fig. 1

Y. pestis pCD1-dependent inhibition of cytokine secretion by human PMNs. Human PMNs were incubated with E. coli, Y. pestis KIM5 (pCD1+), KIM6 (pCD1−), or KIM5 mutant strains deleted of yopE, -H, -T, -J, -M or ypKA. Uninfected PMNs served as unstimulated controls. Culture supernatant was collected after 12 h (gray circles) or 24 h (white circles) of incubation and assayed by multiplex bead arrays for the concentration of each indicated cytokine. The 24 h timepoint was not done for E. coli. Each circle represents the mean value of results from duplicate or triplicate wells of PMNs from a single donor; the horizontal line indicates the median of these values.