Table 1.

Clinical and pathological features of five colorectal cancer patients.

Model	Gender	Age	Prior Chemotherapy	Location	Histopathology				Mutational Status					p16 Methylation Status	Microsatellite Instability Status
					Type	TNM	Stage	Degree of Tumor Differentiation (Grade)	KRAS	BRAF	PIK3CA	APC	TP53
UM-CRM 12-1159	M	51	Unkn	Liver	ADC	Unkn	Unkn	Moderate	WT	WT	H1047R	WT	p.Y102C	Unkn	Unkn
UM-CRM 13-180	F	72	No	Left ovary	ADC	pT3N1aM1a	IVA	Moderate	G12V	WT	WT	WT	p.R248W	Unmethylated	MSS
UM-CRC 13-983	F	69	No	Right/Left colon	ADC	pT3N1c	IIIB	Moderate	WT	V600E	WT	Unkn	p.A6V	Methylated	MSI
UM-CRC 13-1333	F	53	No	Sigmoid colon	ADC	pT3N1b	IIIB	Moderate	G12D	WT	Q546L	p.R1432X	WT	Unmethylated	MSS
UM-CRC 14-136	M	54	No	Right colon	MUC	pT3N0	IIA	Moderate	Q61H	WT	E542K	Unkn	Unkn	Unmethylated	MSS

Abbreviations: ADC = Adenocarcinoma; MSI = Microsatellite instable; MSS = Microsatellite stable; MUC = mucinous; Unkn = Unknown; WT = Wild type