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. Author manuscript; available in PMC: 2017 Jan 1.
Published in final edited form as: Microbes Infect. 2015 Sep 15;18(1):48–56. doi: 10.1016/j.micinf.2015.08.018

Fig. 4. Hepatic levels of P. berghei ANKA 18S rRNA and hepcidin in hemoglobin deficientmice.

Fig. 4

(A) hemoglobin deficient mice (hbd) (n=4) were infected in separate biologic replicates with 15,000 P. berghei ANKA sporozoites and the hepatic parasite load (18s) and hepcidin was quantified by qRT-PCR, then normalized to mouse hprt expression. Wild type mice C57BL6 (B6) were used as controls. The parasite load in hbd was similar compared to control mice (p-value = 0.21). Hepcidin normalized levels were also not different (p-value = 0.41). Mean and S.E.M. are shown. (B) Survival curves for lethal blood stage P. yoelii infection in hbd mice (black line and wild type mice gray dotted line (n=4).