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. Author manuscript; available in PMC: 2017 Mar 1.
Published in final edited form as: Biomaterials. 2015 Dec 18;81:169–180. doi: 10.1016/j.biomaterials.2015.12.009

Figure 7. Immunohistochemical analysis of brain sections for hippocampus swelling.

Figure 7

Following embolic stroke, animals received different treatments at 3 h, and brains were collected at 48 h post stroke. Brain sections were stained for GFAP. (A) Animals treated with tPA + nano-CAT/SOD show reduced swelling in the hippocampus than untreated and tPA alone treated animals. (B) Ratio of the ipsilateral to contralateral hippocampal areas showed reduced hippocampal swelling in tPA + CAT/SOD treated than in other groups. Data as mean ± s.e.m, naïve = 2, other groups = 3 animals in each group. p = 0.06 for untreated vs. tPA+ nano-CAT/SOD treated; p = 0.13 for tPA alone vs. tPA+ nano-CAT/SOD treated.