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. 2016 Jan 21;22(3):1139–1159. doi: 10.3748/wjg.v22.i3.1139

Table 2.

Outcomes related to different kind of lymphadenectomies

Ref.	Year	Country	Type of study	N° pts	Perioperative mortality (%)						Overall morbidity (%)						Overall survival (%)
					D1	D1+	D2	D2+	D3	P value	D1	D1+	D2	D2+	D3	P value	D1	D1+	D2	D2+	D3	P value
[34]	1999	Holland	RCT	711	4	-	10	-	-	0.004	25	-	43	-	-	< 0.0001	45	-	47	-	-	NS
[35,36]	1996	United Kingdom	RCT	400	6.5	-	13	-	-	0.04	28	-	46	-	-	< 0.001	35	-	33	-	-	NS
[35,36]	1999	United Kingdom	RCT	400	6.5	-	13	-	-	0.04	28	-	46	-	-	< 0.001	35	-	33	-	-	NS
[23,24]	1998	Italy	Prospective	191	-	-	3.1	-	-	-	-	-	20.9	-	-	-	-	-	55	-	-	-
[23,24]	2004	Italy	Prospective	191	-	-	3.1	-	-	-	-	-	20.9	-	-	-	-	-	55	-	-	-
[37]	2004	Italy	RCT	162	1.3	-	0	-	-	NS	10.5	-	16.3	-	-	NS
[42,43]	2004	China	RCT	221	0	-	-	-	0	NS	7.3	-	-	-	17.1	0.012	53.6	-	-	-	59.5	0.041
[42,43]	2006	Taiwan	RCT	221	0	-	-	-	0	NS	7.3	-	-	-	17.1	0.012	53.6	-	-	-	59.5	0.041
[28,44]	2004	Japan	RCT	523	-	-	0.8	0.8	-	NS	-	-	20.9	28.1	-	NS	-	-	69.2	70.3	-	NS
[28,44]	2008	Japan	RCT	523	-	-	0.8	0.8	-	NS	-	-	20.9	28.1	-	NS	-	-	69.2	70.3	-	NS
[22]	2007	Japan	RCT	275	-	-	4.9	2.2	-	NS	-	-	27.7	21.6	-	NS	-	-	-	-	-	-
[30]	2010	Holland	Prospective	711	-	-	-	-	-	-	-	-	-	-	-	-	21	-	29	-	-	NS
[39]	2010	Italy	RCT	267	3	-	2.2	-	-	NS	12	-	17.9	-	-	NS	-	-	-	-	-	-
[21]	2015	Italy	Retrospective		-	-	4	-	2.4	NS	-	-	-	-	-	-	-	-	-	-	-	-

Pts: Patients; RCT: Randomized controlled trials.