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. 2016 Jan 14;22(2):833–841. doi: 10.3748/wjg.v22.i2.833

Table 2.

CCL20 and CCR6 data in colorectal cancer available in the literature

Author Year Cell-lines Clinical samples Animal model CCL20 determination CCR6 determination Functional assays Ref.
Rossi 1997 Yes No No SB, NB No No [8]
Izadpanah 2001 Yes Yes No IHC, PCR, ELISA IHC, PCR No [27]
Fujiie 2001 Yes No No ELISA, PCR No No [28]
Kwon 2002 Yes No No ELISA, PCR No No [29]
Dellacasagrande 2003 No Yes Yes No PCR AA [43]
Yang 2005 Yes No No No FC, CM cAMP, PP, CF [32]
Brand 2006 Yes Yes No PCR, IHC PCR, IHC PA, WA, APA [33]
Ghadjar 2006 No Yes No No IHC No [34]
Rubie 2006 No Yes No PCR, ELISA PCR, WB No [35]
Liu 2011 Yes No Yes IF, WB, PCR FC, IF No [51]
Vicinus 2012 Yes No No PCR, ELISA miR, LUC [42]
Hu 2013 No Yes No No IHC No [38]
Frick 2013 No Yes No PCR, ELISA, IHC PCR, IHC No [37]
Vicinus 2013 No Yes No PCR, ELISA, IHC No No [41]
Nandi 2014 Yes Yes Yes ELISA, IHC IHC, PCR, WB No [39]

SB: Southern blot; NB: Northern blot; PCR: Polymerase chain reaction; IHC: Immunohistochemistry; PA: Proliferation assay; ELISA: Enzyme-linked immunosorbent assay; AA: Actin assay; FC: Flow-cytometry; CM: Confocal microscopy; cAMP: cAMP assay; PP: Protein phosphorylation; CF: Calcium flux; WA: Wounding assay; APA: Apoptosis assay; WB: Western blot; IF: Immunofluorescece staining; miR: miRNA assay; LUC: Dual luciferase reporter assay.