Table 2.

Extent of exposure to pirfenidone

	Integrated population (N=1299)
Duration of treatment, years
Median (range)	1.7 (>0 to 9.9)
>0 to <1	404 (31.1%)
1 to <2	350 (26.9%)
2 to <3	118 (9.1%)
3 to <4	102 (7.9%)
≥4	325 (25.0%)
Person exposure years (PEY)*	3160
Daily dose, mg†
Mean (SD)	2053.8 (484.9)
Median (range)	2270.4 (25–3600)
>0 to ≤1800	295 (22.7%)
>1800 to ≤2200	228 (17.6%)
>2200 to 2600	736 (56.7%)
>2600	19 (1.5%)
Missing	21 (1.6%)

*One PEY is the equivalent of one patient exposed to study drug for 1 year; total PEY is the sum of the PEY of each patient.

†Calculated over the total duration of use, excluding the 2-week titration period.