Table 3.
A summary of case series reporting the association between oxaliplatin and sinusoidal dilation
| Study | Number of patients | Sinusoidal dilation | Greater morbidity | Greater mortality |
|---|---|---|---|---|
| Vauthey et al20 | 79 | 15 of 79 patients (19%) | No | No |
| Mehta et al19 | 70 | 43 of 70 patients (61%) | No | No |
| Aloia et al | 52 | 10 of 52 patients (19%) | Yes* | No |
| Kandutsch et al12 | 47 | 11 of 47 patients (23%) | No | No |
| Rubbia-Brandt et al25 | 43 | 34 of 43 patients (78%) | Not available | Not available |
| Pawlik et al21 | 31 | 3 of 31 patients (10%) | No | No |
| Nakano et al16 | 90 | 38 of 90 patients (42%) | Yes | No |
*Aloia et al found a non-statistically significant trend towards increased morbidity.