Fig. 2.

Thyroid echogenicity (a) and thyroid function (b) in patients randomized to Semet (80 or 160 µg) or placebo. Intragroup differences were tested with paired t test and intergroup differences with one-way ANOVA test. p < 0.05: statistically significant. a Echogenicity defined as mean gray-scale pixels, in a spectrum ranging from 0 (corresponding to black) to 255 (corresponding to white). No significant difference was observed within and between the groups. b Two patients developed subclinical hypothyroidism in the placebo group compared to 1 patient in each Semet group.