Table 4.
Overall incidence rates of WHO Stage 3 and 4 conditions stratified by age, gender, BMI, baseline CD4 count and region
| WHO Stage 3 condition | WHO Stage 4 condition | |||
|---|---|---|---|---|
|
|
|
|||
| Incidence per 100 person-years (95% CI) | p* | Incidence per 100 person-years (95% CI) | p* | |
| Age (years) | ||||
| >50 | 12.80 (10.63, 15.28) | <0.001 | 5.83 (5.32, 6.38) | 0.52 |
| 15 to 50 | 8.10 (6.45, 10.07) | 6.05 (5.59, 6.54) | ||
| Gender | ||||
| Male | 12.96 (12.26, 13.69) | <0.001 | 7.98 (7.42, 8.58) | p<0.001 |
| Female | 7.94 (7.44, 8.55) | 3.92 (3.38, 4.74) | ||
| BMI (kg/m2) | ||||
| <18.5 | 10.97 (10.33, 11.64) | p<0.001 | 6.89 (6.37, 7.44) | p<0.001 |
| 18.5 to 25 | 6.22 (5.70, 6.78) | 2.97 (2.64, 3.33) | ||
| >25 | 0.29 (0.17, 0.44) | 0.24 (0.09, 0.42) | ||
| Missing | 3.42 (3.02, 3.84) | 1.78 (1.49, 2.10) | ||
| Baseline CD4 count (cells/mm3) | ||||
| <200 | 10.24 (9.62, 10.89) | p<0.001 | 6.30 (5.77, 6.84) | p<0.001 |
| 200 to 499 | 2.51 (2.13, 2.95) | 0.95 (0.76, 1.17) | ||
| ≥500 | 0.21 (0.09, 0.37) | 0.12 (0.05, 0.22) | ||
| Missing | 7.94 (7.37, 8.53) | 4.51 (95% CI: 4.06, 5.00) | ||
| Region | ||||
| Africa | 16.09 (15.28, 16.91) | p<0.001 | 7.80 (7.23, 8.40) | p<0.001 |
| Asia | 4.60 (4.24, 4.98) | 3.96 (3.59, 4.35) | ||
| Europe | 0.21 (0.06, 0.39) | 0.12 (0.04, 0.26) | ||
*
Bonferroni-adjusted p-value; BMI, body mass index; CI, confidence interval.