Figure 6.

In silico anti‐CD3 treatment result in a lower rate of neuronal death, but a higher number of total neurons killed for some efficacies greater than 80%: (a) EAE was induced at day 0 followed by administration of anti‐CD3 at day 4. (b) The number of neurons killed per hour. (c) Cumulative count of neurons killed for varying efficacies of anti‐CD3 treatment. 100% efficacy blocks all TCR:MHCpeptide bindings, 50% blocks half of all binding events, and 0% represents the control. Figure adopted from Read et al.⁴¹