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| Cmpd 18 |
Abiraterone |
|||
|---|---|---|---|---|
| In vitro assay | Human | Cyno | Human | Cyno |
| CYP17A1 SPA | 19 | 4 | 11 | 2 |
| IC50 (nM) | ||||
| Hydrox/Lyase | 10 | 11 | 3 | 2 |
| Adrenal SPA IC50 (nM) | 20 | 2 | 21 | 3 |
| CYP21A2 IC50 (nM) | >7500 | >7500 | 1050 | 149 |
| CYP11B1 IC50 (nM) | >7500 | >7500 | 872 | 2460 |
