Table 4. Pharmacokinetic Parameters in Cyno for Cmpd 18a.
po dose (mg kg–1) | 4 |
iv dose (mg kg–1) | 2 |
Cmax (μM), po | 3.0 ± 1.1 |
Tmax (h), po | 1.3 ± 0.7 |
AUC (μM·h), po | 12.3 ± 4.0 |
Cl, (mL min–1 kg–1), iv | 19.0 ± 4.8 |
Vss (L/kg), iv | 4.4 ± 1.9 |
F (%) | 97 ± 12 |
Values are reported as mean ± standard deviation.