Table 3.
Tyrosine kinase inhibitors in clinical trials as anti-liver fibrosis agents.
TK inhibitors | ClinicalTrials.gov identifier | Recruited parcitipants | Intervention | Study phase | Status |
---|---|---|---|---|---|
Sorafenib | NCT01714609 | Liver cirrhosis participants with portal hypertension | Sorafenib 400mg p.o. twice daily | Phase II | Completed |
Erlotinib | NCT02273362 | Liver cirrhosis participants following HCC resection | Erlotinib p.o. for 7 days | Phase I | Recruiting |