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. 2016 Jan 18;6:300. doi: 10.3389/fphar.2015.00300

Table 3.

Tyrosine kinase inhibitors in clinical trials as anti-liver fibrosis agents.

TK inhibitors ClinicalTrials.gov identifier Recruited parcitipants Intervention Study phase Status
Sorafenib NCT01714609 Liver cirrhosis participants with portal hypertension Sorafenib 400mg p.o. twice daily Phase II Completed
Erlotinib NCT02273362 Liver cirrhosis participants following HCC resection Erlotinib p.o. for 7 days Phase I Recruiting