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Minimum inhibitory concentration (MIC) of thiazole compounds against methicillin-resistant Staphylococcus aureus (MRSA) ATCC 43300.
| Analogue | MIC (μg/mL) |
|---|---|
| 1 (lead) | 1.3 |
| 5 | 1.4 |
| 7 | 12.6 |
| 9 | >35.1 |
| 10 | >45.8 |
| 11 | >42.4 |
| 12 | 44.5 |
| 13 | 44.2 |
| 15 | >37.0 |
| 16 | >38.3 |
| 19 | >36.9 |
| 21b | >39.8 |
| 21c | >46.2 |
| 22a | >46.7 |
| 22b | 5.9 |
| 22c | 3.3 |
| 22d | 6.3 |
| 24 | >43.9 |
| 25 | 1.6 |
