Table 1.
Clinical Characteristics of Screened Probands
|
Probands with Deletions (40 F and 50 M) |
Probands with Duplications (16 F and 20 M) |
|||||
|---|---|---|---|---|---|---|
| Median | Range | Number Reported | Median | Range | Number Reported | |
| Age (years) | 7.83 | 0.83–20.75 | 89/90 | 5.83 | (1.42–23.42) | 35/36 |
| FSIQ | 86 | 46–122 | 87/90 | 77 | (28–114) | 33/36 |
| FSIQ decrement | 25.5 | −9–68.5 | 49/90 | 22 | (6.5–89) | 23/36 |
| Social Responsiveness Scale score | 74.5 | 37–90 | 78/90 | 76 | (42–90) | 25/36 |
| Autism Diagnostic Interview Revised score | 11 | 2–30 | 60/90 | 11.5 | (2–26) | 18/36 |
| Head circumference (cm) | 54 | 45–59.7 | 86/90 | 51.05 | (44.4–58) | 34/36 |
| BMI | 19.2 | 13.35–37.13 | 86/90 | 16.17 | (13.36–28.37) | 34/36 |
| Number of diagnosesa | 3 | 1–5 | 80/90 | 2 | (1–5) | 32/36 |
Abbreviations are as follows: F, female; M, male.
a
This includes ASD, ADHD, communication disorders, anxiety disorders, mood disorders, intellectual disability, tic disorders, elimination disorders, learning disorders, and behavioral disorders, totaling 27 diagnostic codes. 21/89 deletion-carrying probands and 8/35 duplication-carrying probands for whom data was reported have been diagnosed with clinical autism.