Figure 5. Transcription factor expression by A. actinomycetemcomitans-induced T lymphocytes. T-bet (Th1), GATA-3 (Th2), RORC2 (Th17), and Foxp3 (T-regulatory) mRNA expression in T lymphocytes stimulated by dendritic cells primed at a MOI=102 with the A. actinomycetemcomitans strains ATCC® 43717™ (serotype a), ATCC® 43718™ (serotype b), and ATCC® 43719™ (serotype c). For relative expression, the transcription factor mRNA expression in T lymphocytes exposed to non-induced dendritic cells was considered as 1, as a reference for fold-change in expression (n.i.). Data are represented as fold-change for 8 independent experiments. Each experiment was performed in duplicate. Comparisons were done between the different A. actinomycetemcomitans serotypes (*p<0.05).
