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. 2016 Jan 13;10:297–313. doi: 10.2147/DDDT.S80625

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© 2016 Sidahmed et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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Macroscopic evaluation.

Notes: The macroscopic appearance of the gastric mucosa of the rats of the normal control (A) exhibit the intact mucosal appearance with no lesions as seen. Whereas, the rats of the ulcer control pretreated with only Tween 80 (B) showed that the ethanol-induced severe visible lesions to the gastric mucosa appeared as elongated bands of hemorrhage (black arrows). However, the pretreatment with omeprazole at 20 mg/kg (C) showed mild lesions as seen in the gastric mucosa (black arrow). The pretreatment with BM at 5 mg/kg (D) showed moderate lesions as seen in the gastric mucosa (black arrows). The pretreatment with BM at 10 mg/kg (E) showed very mild lesions as seen in the gastric mucosa (black arrow). The pretreatment with BM at 20 mg/kg (F) showed mild lesions as seen in the gastric mucosa (black arrow) (magnification: ×1.8).

Abbreviation: BM, β-mangostin.