Table 1.
Characteristics of patients with and without nonalcoholic fatty liver disease
| Variables | NAFLD patients (N=163) |
Controls (N=77) |
P-value |
|---|---|---|---|
| Age (years) | 54±11 | 55±11 | 0.470 |
| Male (%) | 36.2 | 28.6 | 0.244 |
| Waist circumference (cm) | 103±12 | 88±11 | <0.001 |
| BMI (kg/m2) | 30±5.5 | 25.64±3.8 | <0.001 |
| Smoking (%) | 27.1 | 23.5 | 0.584 |
| eGFR (mL/min/1.73 m2) | 97±27 | 101±23 | 0.399 |
| Hypertension (%) | 65.6 | 46.8 | 0.008 |
| Office SBP (mmHg) | 149±17 | 145±16 | 0.070 |
| Office DBP (mmHg) | 90±11 | 88±10 | 0.160 |
| 24-hour mean SBP (mmHg) | 131±12 | 126±12 | 0.002 |
| 24-hour mean DBP (mmHg) | 80±9.50 | 78±9.11 | 0.104 |
| Daytime mean SBP (mmHg) | 136±13.04 | 131±12.87 | 0.006 |
| Daytime mean DBP (mmHg) | 85±10 | 83±9.8 | 0.182 |
| Nighttime mean SBP (mmHg) | 120±14.00 | 113.4±18.00 | 0.004 |
| Nighttime mean DBP (mmHg) | 71±11 | 69±10 | 0.284 |
| Morning mean SBP (mmHg) | 131±14 | 125±17 | 0.013 |
| Morning mean DBP (mmHg) | 81±11 | 79±11 | 0.153 |
| White-coat hypertension (%) | 20.9 | 26 | 0.435 |
| AST (IU/L) | 22±9.70 | 19.10±5.51 | 0.023 |
| ALT (IU/L) | 29.3±23 | 22.40±21 | 0.001 |
| GGT (IU/L) | 24.8±16.3 | 15.6±8.2 | <0.001 |
| ALP (IU/L) | 97.41±105.44 | 81.33±47.23 | 0.238 |
| CHOL (mg/dL) | 217±39 | 210±42 | 0.243 |
| LDL (mg/dL) | 138±36 | 136±40 | 0.729 |
| HDL (mg/dL) | 56.34±19.85 | 63.60±17.36 | 0.011 |
| TRIGL (mg/dL) | 130±65 | 94±51 | <0.001 |
| Hs-CRP (mg/L) | 1.32±2.32 | 0.84±1.29 | 0.057 |
| GLU (mg/dL) | 95.66±12.52 | 90.89±8.77 | 0.001 |
Notes: Noncontinuous variables are given as percentages. Continuous variables are presented as mean ± SD. Upper reference limits are 45 IU/L for AST, 45 IU/L for ALT, 55 IU/L for GGT, 150 IU/L for ALP, 200 mg/dL for CHOL, 140 mg/dL for LDL, 160 mg/dL for TRIGL, 5 mg/L for Hs-CRP, and 110 mg/dL for GLU in our laboratory. Lower reference limit is 35 mg/dL for HDL in our laboratory.
Abbreviations: NAFLD, nonalcoholic fatty liver disease; BMI, body mass index; eGFR, estimated glomerular filtration rate; SBP, systolic blood pressure; DBP, diastolic blood pressure; AST, aspartate aminotransferase; ALT, alanine aminotransferase; GGT, gamma glutamyl transpeptidase; ALP, alkaline phosphatase; CHOL, cholesterol; LDL, low-density lipoprotein; HDL, high-density lipoprotein; TRIGL, triglycerides; Hs-CRP, high-density c-reactive protein; GLU, glucose serum fast; SD, standard deviation.