Table 4.
Variables associated with nonalcoholic fatty liver disease in men
| Variables | B | OR | 95% CI | P-value |
|---|---|---|---|---|
| Bivariate analysis | ||||
| Age (years) | −0.043 | 0.958 | 0.909–1.009 | 0.104 |
| Waist circumference (cm) | 0.141 | 1.152 | 1.066–1.244 | ,0.001 |
| BMI (kg/m2) | 0.280 | 1.323 | 1.114–1.570 | 0.001 |
| Smoking (yes) | 0.235 | 1.265 | 0.391–4.097 | 0.695 |
| eGFR (mL/min/1.73 m2)a | 0.011 | 1.011 | 0.692–1.477 | 0.957 |
| Hypertension (yes) | −0.678 | 0.508 | 0.131–1.972 | 0.327 |
| Office SBP (mmHg)b | 0.679 | 1.972 | 1.972–7.668 | 0.634 |
| Office DBP (mmHg) | 0.014 | 1.014 | 0.971–1.060 | 0.521 |
| 24-hour mean SBP (mmHg) | 0.031 | 1.031 | 0.987–1.077 | 0.170 |
| 24-hour mean DBP (mmHg) | 0.010 | 1.010 | 0.959–1.063 | 0.712 |
| Daytime mean SBP (mmHg) | 0.021 | 1.022 | 0.981–1.063 | 0.298 |
| Daytime mean DBP (mmHg) | 0.006 | 1.006 | 0.959–1.055 | 0.814 |
| Nighttime mean SBP (mmHg) | 0.018 | 1.018 | 0.983–1.054 | 0.313 |
| Nighttime mean DBP (mmHg) | 0.010 | 1.010 | 1.038–1.059 | 0.967 |
| Morning mean SBP (mmHg) | 0.011 | 1.011 | 0.975–1.049 | 0.544 |
| Morning mean DBP (mmHg) | 0.006 | 1.006 | 0.956–1.059 | 0.810 |
| White-coat hypertension (yes) | 0.980 | 2.633 | 0.737–9.622 | 0.295 |
| AST (IU/L) | 0.060 | 1.062 | 0.987–1.142 | 0.093 |
| ALT (IU/L) | 0.008 | 1.008 | 0.988–1.029 | 0.443 |
| GGT (IU/L) | 0.062 | 1.064 | 1.004–1.127 | 0.035 |
| ALP (IU/L) | −0.001 | 0.999 | 0.988–1.009 | 0.792 |
| CHOL (mg/dL) | −0.007 | 0.993 | 0.980–1.006 | 0.262 |
| LDL (mg/dL) | −0.010 | 0.990 | 0.975–1.005 | 0.205 |
| HDL (mg/dL) | −0.025 | 0.975 | 0.943–1.009 | 0.149 |
| TRIGL (mg/dL) | 0.008 | 1.008 | 0.998–1.018 | 0.135 |
| Hs-CRP (mg/L)c | 0.371 | 1.449 | 0.503–4.172 | 0.492 |
| GLU (mg/dL) | 0.037 | 1.038 | 0.991–1.087 | 0.119 |
| Multivariate logistic regressiona | ||||
| BMI (kg/m2) | 0.213 | 1.237 | 1.047–1.461 | 0.012 |
| GGT (IU/L) | 0.055 | 1.056 | 0.991–1.127 | 0.093 |
Notes: Odds ratio and 95% CI adjusted by the variables with P<0.100 in bivariate analysis. BMI and waist circumference were not included in the same model because they are continuous variables with a correlation coefficient higher than 0.7. The same applies to 24-hour mean SBP and daytime mean SBP, 24-hour mean SBP and nighttime mean SBP, and 24-hour mean SBP and morning mean SBP. Upper reference limits are 45 IU/L for AST, 45 IU/L for ALT, 55 IU/L for GGT, 150 IU/L for ALP, 200 mg/dL for CHOL, 140 mg/dL for LDL, 160 mg/dL for TRIGL, 5 mg/L for Hs-CRP, and 110 mg/dL for GLU in our laboratory. Lower reference limit is 35 mg/dL for HDL in our laboratory.
The variable eGFR was transformed using square root;
the variable office SBP was logarithmically transformed;
the variable Hs-CRP was logarithmically transformed.
Abbreviations: B, regression coefficient; OR, odds ratio; CI, confidence interval; BMI, body mass index; eGFR, estimated glomerular filtration rate; SBP, systolic blood pressure; DBP, diastolic blood pressure; AST, aspartate aminotransferase; ALT, alanine aminotransferase; GGT, gamma glutamyl transpeptidase; ALP, alkaline phosphatase; CHOL, cholesterol; LDL, low-density lipoprotein; HDL, high-density lipoprotein; TRIGL, triglycerides; Hs-CRP, high-density c-reactive protein; GLU, glucose serum fast.