Table 5.
Variables | NAFLD patients (N=104) |
Controls (N=55) |
P-value |
---|---|---|---|
Age (years) | 56±10 | 55±11 | 0.592 |
Waist circumference (cm) | 101±13 | 87±11 | <0.001 |
BMI (kg/m2) | 30±6 | 25±4 | <0.001 |
Smoking (%) | 23.6 | 22.0 | 0.830 |
eGFR (mL/min/1.73 m2) | 84±2 | 84.5±2 | 0.732 |
Hypertension (%) | 75.8 | 21.5 | 0.001 |
Office SBP (mmHg) | 146±16 | 143±17 | 0.226 |
Office DBP (mmHg) | 89±10 | 87±11 | 0.298 |
24-hour mean SBP (mmHg) | 129±11 | 124±13 | 0.011 |
24-hour mean DBP (mmHg) | 78±8 | 76±9 | 0.156 |
Daytime mean SBP (mmHg) | 134±11 | 129±13 | 0.017 |
Daytime mean DBP (mmHg) | 83±9 | 81±10 | 0.267 |
Nighttime mean SBP (mmHg) | 119±12 | 111±20 | 0.004 |
Nighttime mean DBP (mmHg) | 70±10 | 68±10 | 0.294 |
Morning mean SBP (mmHg) | 130±13 | 123±17 | 0.012 |
Morning mean DBP (mmHg) | 80±10 | 77±12 | 0.168 |
White-coat hypertension (%) | 26 | 34.5 | 0.291 |
AST (IU/L) | 20±6 | 19±5 | 0.132 |
ALT (IU/L) | 23±11 | 19±10 | 0.018 |
GGT (IU/L) | 22±14 | 14±6 | <0.001 |
ALP (IU/L) | 103±128 | 78±44 | 0.183 |
CHOL (mg/dL) | 220±39 | 205±39 | 0.031 |
LDL (mg/dL) | 138±39 | 131±37 | 0.274 |
HDL (mg/dL) | 61±21 | 67±17 | 0.084 |
TRIGL (mg/dL) | 126±57 | 89±50 | <0.001 |
Hs-CRP (mg/L) | 1.37±2.62 | 0.88±1.90 | 0.283 |
GLU (mg/dL) | 94±10 | 90±9 | 0.019 |
Notes: Data are presented as mean ± standard deviation. Upper reference limits are 45 IU/L for AST, 45 IU/L for ALT, 55 IU/L for GGT, 150 IU/L for ALP, 200 mg/dL for CHOL, 140 mg/dL for LDL, 160 mg/dL for TRIGL, 5 mg/L for Hs-CRP, and 110 mg/dL for GLU in our laboratory. Lower reference limit is 35 mg/dL for HDL in our laboratory.
Abbreviations: NAFLD, nonalcoholic fatty liver disease; BMI, body mass index; eGFR, estimated glomerular filtration rate; SBP, systolic blood pressure; DBP, diastolic blood pressure; AST, aspartate aminotransferase; ALT, alanine aminotransferase; GGT, gamma glutamyl transpeptidase; ALP, alkaline phosphatase; CHOL, cholesterol; LDL, low-density lipoprotein; HDL, high-density lipoprotein; TRIGL, triglycerides; Hs-CRP, high-density c-reactive protein; GLU, glucose serum fast.