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. 2016 Jan 12;11:213–221. doi: 10.2147/IJN.S97496

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© 2016 Yousaf et al. This work is published and licensed by Dove Medical Press Limited

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Mean plasma level vs time profiles of fenofibric acid in rats after oral administration of free powder, solid dispersion, and electrosprayed nanospherules.

Notes: Each dose was equivalent to 20 mg/kg fenofibrate. The electrosprayed nanospherules and the solid dispersion were composed of fenofibrate, PVP, and Labrafil M 2125 at the weight ratio of 1:4:0.5. Each value represents the mean ± SD (n=6). *P<0.05 compared with the free drug.

Abbreviations: PVP, polyvinylpyrrolidone; SD, standard deviation.