Table 2.
Relationship between telomerase reverse transcriptase methylation and clinicopathological characteristics of 116 GC patients
| Characteristics | Hypermethylation, n (%) | Non-hypermethylation, n (%) | P-value |
|---|---|---|---|
| Number of cases, n (%) | 38 (32.8) | 78 (67.2) | – |
| Age | |||
| <60 years | 21 (55.3) | 43 (55.1) | 0.989 |
| ≥60 years | 17 (44.7) | 35 (44.9) | |
| Sex | |||
| Male | 30 (78.9) | 59 (75.6) | 0.692 |
| Female | 8 (21.1) | 19 (24.4) | |
| Histological grade | |||
| Well/moderate | 9 (23.7) | 17 (21.8) | 0.819 |
| Poor | 29 (76.3) | 61 (78.2) | |
| Gastric wall invasion | |||
| T1–2 | 3 (7.9) | 20 (25.6) | 0.024 |
| T3–4 | 35 (92.1) | 58 (74.4) | |
| Lymph node metastasis | |||
| N0–N2 | 8 (21.1) | 37 (47.4) | 0.006 |
| N3 | 30 (78.9) | 41 (52.6) | |
| Lymphovascular/neural invasion | |||
| Negative | 6 (15.8) | 27 (34.6) | 0.035 |
| Positive | 32 (84.2) | 51 (65.4) | |
Abbreviation: GC, gastric cancer.