Table 2.
1q21 amplification and correlation with laboratory findings and patients survival
| Characteristics | All patients | Groups
|
|||
|---|---|---|---|---|---|
| 1q21 gain negative | Patients with three copies of 1q21 | Patients with four copies of 1q21 | P-value | ||
| ESR (mm/h) mean; range | 94.00 (3–168) | 94.21 (6–157) | 92.25 (3–168) | 99.00 (44–125) | 0.947** |
| CRP (mg/L) mean; range | 9.99 (2.1–113) | 9.90 (2.1–58.2) | 8.13 (3.16–58.7) | 15.40 (2.97–113) | 0.501** |
| β2-microglobulin (mg/L) mean; range | 9.94 (1.67–134) | 11.84 (1.67–134) | 5.86 (2–20.5) | 11.63 (2.73–24.9) | 0.272** |
| Hemoglobin (g/L) mean; range | 86.62 (41–162) | 88.15 (43–137) | 86.76 (41–162) | 79.82 (59–123) | 0.629** |
| Platelet (109/L) mean; range | 168.88 (43–481) | 174.33 (43–481) | 172.46 (67–312) | 137.45 (49–337) | 0.406** |
| Albumin (g/L) mean; range | 31.64 (15.4–60.8) | 31.02 (15.4–45.4) | 33.14 (15.8–60.8) | 30.0 (21.4–44.4) | 0.493** |
| Mortality (dead/alive) | 21/65 | 9/37 | 8/21 | 4/7 | 0.450* |
Notes: Statistical tests used:
*
Pearson chi-square,
**
one-way ANOVA.
Abbreviations: ANOVA, analysis of variance; CRP, C-reactive protein; ESR, erythrocyte sedimentation rate.