Table 3.
Cox (multivariate) analysis of risk factors for PFS and OS
| Variable | PFS
|
OS
|
||||
|---|---|---|---|---|---|---|
| HR | 95% CI | P-value | HR | 95% CI | P-value | |
| Copy number of amp(1q21) | 0.001 | 0.041 | ||||
| Three copies vs two copies | 2.344 | 0.882–6.233 | 0.088 | 1.613 | 0.593–4.386 | 0.349 |
| Four copies vs two copies | 11.341 | 3.037–42.348 | 0.000 | 6.209 | 1.504–25.635 | 0.012 |
| Del(13q14) | 0.850 | 0.342–2.109 | 0.726 | 0.364 | 0.114–1.165 | 0.089 |
| Del(17p13) | 4.864 | 1.403–16.862 | 0.013 | 1.334 | 0.307–5.798 | 0.701 |
| IGH translocation | 1.738 | 0.655–4.612 | 0.267 | 2.353 | 0.803–6.893 | 0.119 |
Abbreviations: CI, confidence interval; HR, hazard ratio; OS, overall survival; PFS, progression-free survival; vs, versus.