Figure 1.

(A) Representative immunohistochemistry figure of low-MECOM expression (left) and high-MECOM expression (right). Slides were observed under ×400 magnification and scale bar represents 50 μm. (B) The mRNA of MECOM was detected by real-time PCR. MECOM mRNA level in GBM tissues was remarkably higher than that in the corresponding adjacent tissues. (C) Expression of MECOM in different GBM cell lines U251MG, A172, U118MG, and U87MG was detected by immunoblotting.

Abbreviations: GBM, glioblastoma multiforme; MECOM, MDS1 and EVI1 complex locus protein EVI1; PCR, polymerase chain reaction; IB, immunoblotting.