Table 2.
Prognostic value of MECOM
| Parameters | Univariate
|
Multivariate
|
P-value# | ||
|---|---|---|---|---|---|
| 1-year survival rate (%) | P-value* | HR | 95% CI | ||
| Age | |||||
| ≤50 | 52.7 | 1 | |||
| >50 | 58.5 | 0.434 | 0.65 | 0.26–1.40 | 0.24 |
| Sex | |||||
| Male | 63.2 | 1 | |||
| Female | 48.1 | 0.308 | 1.54 | 0.70–3.42 | 0.286 |
| KPS | |||||
| <80 | 22.3 | 1 | |||
| ≥80 | 43.5 | 0.793 | 0.92 | 0.43–2.02 | 0.851 |
| Extent of resection | |||||
| Complete | 66.9 | 1 | |||
| Incomplete | 35.9 | 0.028 | 2.67 | 1.17–6.10 | 0.02 |
| MECOM | |||||
| Low | 64.7 | 1 | |||
| High | 20.6 | 0.033 | 2.45 | 1.03–5.82 | 0.042 |
Notes:
*
Means calculated by log-rank test.
#
Means calculated by Cox proportional hazards regression.
Abbreviations: CI, confidence interval; HR, hazard ratio; KPS, Karnofsky Performance Scale; MECOM, MDS1 and EVI1 complex locus protein EVI1.