Table 1.

The usual dose and schedule of chemotherapy regimens

Regimen	Dose and route	Interval and duration
FOLFOX	Oxaliplatin (85 mg/m2 i.v. injection of over 2 h on day 1), leucovorin (200 mg/m2 i.v. injection of over 2 h on day 1 and 2), and 5-FU (400 mg/m2 i.v bolus injection, followed by 600 mg/m2 continuous i.v. injection on day 1 and 2) [FOLFOX-4], or Oxaliplatin (85 mg/m2 i.v. injection of over 2 h on day 1), leucovorin (400 mg/m2 i.v. injection of over 2 h on day 1), and 5-FU (400 mg/m2 i.v. bolus injection on day 1, followed by 2400 mg/m2 continuous i.v. injection over 46 hr) [mFOLFOX-6].	Every 2 weeks for 12 cycles
CAPOX	Capecitabine (1000 mg/m2 orally administered twice a day for 2 weeks, followed by a one-week rest) and oxaliplatin (130 mg/m2 i.v. injection over 2 h on day 1).	Every 3 weeks for 8 cycles
5-FU/LV	5-FU (425mg/m2 intravenous injection for 5 days) and leucovorin (20 or 200 mg/m2 i.v. injection for 5 days) [FL], or Leucovorin (400mg/m2 i.v. injection over 2 hr) and 5-FU (400 mg/m2 i.v. bolus injection on day 1, followed by 2400 mg/m2 continuous i.v. injection over 46 hr) [LV5FU2]	Every 4 weeks for 6 cycles Every 2 weeks for 12 cycles
Capecitabine	1250 mg/m2 orally administered twice a day for 2 weeks, followed by a one-week rest.	Every 3 weeks for 8 cycles
UFT/LV	Uracil-tegafur (100 mg/m2 orally administered three times a day) with or without leucovorin (30 mg orally administered three times a day on days 1-28, followed by a one-week break).	Every 5 weeks for 5 cycles

FOLFOX: leucovorin, 5-fluorouracil, and oxaliplatin; 5-FU/LV: 5-fluorouracil with leucovorin;

CAPOX: capecitabine and oxaliplatin; UFT/LV: uracil-tegafur and leucovorin