Table 1.

The characteristics of the included studies on RFC1 G80A polymorphism and cancer risk

Author	Year	Ethnicity	Country	Cancer type	Sample size	Cases			Controls
					Cases/Controls	GG	GA	AA	GG	GA	AA
Whetstine[44]	2001	Caucasian	USA	ALL	54/51	10	24	20	9	25	17
Skibola[45]	2004	Caucasian	USA	non-Hodgkin lymphoma	334/729	109	158	67	266	331	132
Ulrich[22]	2005	Mixed	USA	colorectal cancer	1600/1962	513	788	299	585	976	401
Lightfoot[46]	2005	Caucasian	USA	non-Hodgkin lymphoma	589/755	199	277	113	263	369	123
Wang[26]	2006	Asian	China	oesophageal cancer	216/673	66	67	83	193	313	167
Wang[26]	2006	Asian	China	gastric cancer	633/673	177	242	214	193	313	167
Moore[27]	2007	Caucasian	Spain	bladder cancer	1084/1032	301	520	263	313	500	219
Xu[28]	2007	Caucasian	USA	breast cancer	1066/1108	247	532	287	237	561	310
Gast[47]	2007	Caucasian	Germany	ALL	542/542	125	251	79	178	256	108
Eklof[23]	2008	Caucasian	Sweden	colorectal cancer	219/410	70	93	56	116	190	104
Kotsopoulos[29]	2008	Caucasian	Canada	breast cancer	937/764	304	440	193	243	347	174
Liu[48]	2008	Asian	China	lung cancer	499/504	127	250	122	137	250	117
Sirachainan[32]	2008	Asian	Thailand	central nervous system tumors	73/205	18	38	17	44	104	57
Di[40]	2009	Asian	China	cervical cancer	107/107	31	48	28	18	46	43
de Jonge[49]	2009	Caucasian	Netherland	ALL	241/495	69	120	52	186	241	68
Kurzwelly[50]	2010	Caucasian	Germany	primary central nervous system lymphoma	185/212	68	87	30	76	91	45
Yeoh[51]	2010	Asian	Malaysia-Singapore	ALL	210/319	62	108	40	72	170	77
Curtin[24]	2011	Mixed	USA	colorectal cancer	724/922	226	351	147	280	459	183
Galbiatti[41]	2011	Caucasian	Brazil	head and neck aquamous cell carcinoma	322/531	92	137	93	126	221	184
Jokic[25]	2011	Caucasian	Croatia	colorectal cancer	300/300	85	160	55	90	155	55
Naushad[30]	2011	Asian	India	breast cancer	244/244	87	107	50	96	122	26
Chan[20]	2011	Asian	Singapore	ALL	184/177	43	98	43	61	75	41
Metayer[21]	2011	Caucasian	USA	ALL	348/422	106	188	54	132	205	85
Yang[52]	2011	Asian	China	ALL	361/367	93	172	96	105	191	71
Zhao[53]	2011	Asian	China	ALL	98/135	21	53	24	53	52	30
De Cassia[31]	2012	Caucasian	Brazil	breast cancer	156/156	58	71	27	30	89	37
Silva[38]	2013	Caucasian	Brazil	AML	21/137	4	10	7	49	56	32
Silva[38]	2013	Caucasian	Brazil	ALL	95/137	21	38	36	49	56	32
De Miranda[37]	2014	Caucasian	Brazil	central nervous system tumors	30/92	4	14	12	31	43	18
Karathanasis[54]	2014	Caucasian	Greece	ALL	35/48	9	16	10	15	18	15
Suthandiram[55]	2014	Asian	Malaysia	non-Hodgkin lymphoma	372/722	99	182	91	187	354	181
Montalvao[39]	2015	Caucasian	Brazil	nephroblastoma	77/222	13	38	26	76	103	43
Montalvao[39]	2015	Caucasian	Brazil	central nervous system tumors	64/222	11	33	20	76	103	43

ALL, acute lymphoblast leukemia; AML, acute myeloid leukemia