Table 1.
Clinicopathologic findings in patients with early gas-tric carcinoma with and without lymph node metastasis
| Node-negative | Node-positive | P value | |
| n = 673, (%) | n = 75, (%) | ||
| Age (mean, yr) | 55.7 ± 10.7 | 57.9 ± 10.7 | NS |
| Gender | < 0.05 | ||
| Male | 453 (67.3) | 41 (54.7) | |
| Female | 220 (32.7) | 34 (45.3) | |
| Age (yr) | NS | ||
| ≤ 40 | 71 (10.5) | 5 (6.7) | |
| > 40 | 602 (89.5) | 70 (93.3) | |
| Tumor size (mean, cm) | 2.2 ± 1.45 | 3.1 ± 1.89 | < 0.01 |
| < 2 | 434 (64.5) | 10 (13.3) | < 0.01 |
| 2-3 | 141 (21.0) | 24 (32.0) | |
| > 3 | 98 (14.5) | 41 (54.7) | |
| Tumor location | NS | ||
| Upper | 28 (4.2) | 2 (2.7) | |
| Middle | 200 (29.7) | 18 (24.0) | |
| Lower | 445 (66.1) | 55 (73.3) | |
| Macroscopic appearance | NS | ||
| Protruded | 208 (30.9) | 21 (28.0) | |
| Depressed | 417 (62.0) | 50 (66.7) | |
| Mixed | 48 (7.1) | 4 (5.3) | |
| Stage | < 0.01 | ||
| Ia | 672 (99.9) | ||
| Ib | 65 (86.7) | ||
| II | 6 (8.0) | ||
| IV | 1 (0.1) | 4 (5.3) | |
| Histologic type | < 0.01 | ||
| Differentiated | 348 (51.7) | 24 (32.0) | |
| Undifferentiated | 325 (48.3) | 51 (68.0) | |
| Depth of invasion | < 0.01 | ||
| Mucosa | 363 (53.9) | 14 (18.7) | |
| Submucosa | 310 (46.1) | 61 (81.3) | |
| Operative type | NS | ||
| Total gastrectomy | 62 (9.2) | 8 (10.7) | |
| Proximal gastrectomy | 4 (0.6) | ||
| Distal gastrectomy | 583 (86.8) | 65 (86.7) | |
| Others | 24 (3.4) | 2 (2.7) | |
| Lymph node dissection | < 0.01 | ||
| D1 | 144 (21.4) | 8 (10.7) | |
| D2 | 484 (71.9) | 50 (66.7) | |
| ≥ D3 | 45 (6.7) | 17 (22.7) | |
| Curability | NS | ||
| Curative | 671 (99.7) | 73 (97.3) | |
| Non-curative | 2 (0.3) | 2 (2.7) |
NS, not significant.