Table 2.
Correlation between expression of NF-κBP65 protein, hTERT mRNA and protein and clinicopathological features
Factor | Cases | NF-κB | hTERT | hTERT |
P65 (%) | mRNA (%) | protein (%) | ||
Gender | ||||
Male | 30 | 16 (53.33) | 24 (80.00) | 24 (80.00) |
Female | 11 | 9 (81.82) | 11 (100.00) | 8 (72.73) |
Age (years) | ||||
< 60 | 24 | 14 (58.33) | 21 (87.50) | 20 (83.33) |
≥ 60 | 17 | 11 (64.71) | 14 (82.35) | 12 (70.59) |
Histology (type) | ||||
Intestinal | 16 | 7 (43.75) | 12 (75.00) | 10 (62.50) |
Differentiation | 25 | 18 (72.00) | 23 (92.00) | 22 (88.00) |
Differentiation | ||||
Well | 13 | 3 (23.08)b | 9 (69.23) | 7 (53.85)a |
Poor | 28 | 22 (78.57) | 26 (92.86) | 25 (89.29) |
Lymph node metastasis | ||||
Negative | 16 | 4 (25.00)b | 12 (75.00) | 9 (56.25)a |
Positive | 25 | 21 (84.00) | 23 (92.00) | 23 (92.00) |
Stage | ||||
Early | 12 | 2 (16.67)b | 7 (58.33)b | 5 (41.67)b |
Advanced | 29 | 23 (79.31) | 28 (96.55) | 27 (93.10) |
Tumor size (cm) | ||||
< 5 | 19 | 6 (31.58)b | 14 (73.68) | 13 (68.42) |
≥ 5 | 22 | 19 (86.36) | 21 (95.45) | 19 (86.36) |
Depth of invasion | ||||
m, sm | 10 | 2 (20.00)a | 6 (60.00) | 4 (40.00)a |
ms, ss | 17 | 11 (64.71) | 16 (94.12) | 15 (88.24) |
se, si | 14 | 12 (85.71) | 13 (92.86) | 13 (92.86) |
P < 0.05,
P < 0.01, From comparison in each group of clinicopatho-logic feature by chi-square test or Fisher’s exact test. m: mucosa, sm: submucosa, mp: muscularis propria, ss: subserosa, se: inva-sion to serosa, si: invasion to other organ. Tumor size was de-fined as the largest size in extension on the gastric mucosa.