Table 2.
Multivariate survival analysis in the 50 enrolled HCC patients. Only variables significantly influencing survival at univariate analysis were introduced in the Cox proportional hazard model
| Variables | RR (95%CI) | Likelihood-ratio χ2 | P |
| Assessing single variables | |||
| Surgery | 2.72 (1.59-5.03) | 14.07 | 0.0002 |
| AFP mRNA | 2.00 (0.90-4.82) | 2.83 | NS |
| Moderately or poorly differentiated grade | 1.20 (0.55-2.41) | 0.23 | NS |
| Gross vascular invasion | 0.86 (0.48-1.59) | 0.24 | NS |
| Performance status >1 | 1.21(0.64-2.46) | 0.31 | NS |
| Combining tumor related variables | |||
| Surgery | 5.84 (2.23-17.32) | 13.23 | 0.0003 |
| 1Early HCC | 5.84 (2.23-17.32) | 13.6 | 0.0002 |
| Performance status >1 | 1.18 (0.41-3.09) | 0.11 | NS |
RR: risk ratio; CI: confidence interval.
1
AFP mRNA negative and well-differentiated HCC without gross vascular invasion.