Table 2.
Effect of BPC 157 on pylorus ligation induced gastric ulcer formation (n = 10)
| Administration | Agents | Dosage (ng/kg) | Ulcer (mm2) | Inhibition ratio(%) |
| im | Saline control | 131.2 ± 58.1 | ||
| Excipient control | 130.2 ± 68.2 | |||
| Famotidine | 40 000 | 55.7 ± 46.7 | 57.2b | |
| BPC 157 | 200 | 80.9 ± 22.8 | 37.8b | |
| BPC 157 | 400 | 47.6 ± 27.8 | 63.5b | |
| BPC 157 | 800 | 44.8 ± 19.4 | 65.6b | |
| ig | Saline control | 140.1 ± 78.1 | ||
| Famotidine | 40 000 | 34.1 ± 33.1 | 75.7b | |
| BPC 157 | 200 | 110.5 ± 41.5 | 21.1 | |
| BPC 157 | 400 | 64.1 ± 35.4 | 54.2a | |
| BPC 157 | 800 | 58.6 ± 37.6 | 58.2b |
a
P < 0.05,
b
P < 0.01 vs excipient control (im) or saline control (ig).