Table 1.
Predicted binding score and probable site of metabolism of various insecticides by CYP6P4.
| Insecticide | Structure | PLANTSPLP score | Distance to heme iron (Å) | Predicted site of metabolism |
|---|---|---|---|---|
| 1R-cis permethrin ZINC01850376 |
 |
- 72.99 | 4.1 | 4′ spot of the phenoxy ring |
| Bifenthrin ZINC02516821 |
 |
−79.06 | 4.7 | C-6 of the benzyl ring |
| Deltamethrin ZINC01997854 |
 |
−68.09 | 4.2 | trans-methyl group of cyclopropane |
| λ-cyhalothrin ZINC013827939 |
 |
−71.25 | 4.8 | 4′ spot of the phenoxy ring |
| Etofenprox ZINC02558051 |
 |
−70.16 | 3.8 | -CH3 of 2-methylpropoxy moiety |
| Bendiocarb ZINC02015426 |
 |
−45.74 | 3.4 | C5/6 of the aromatic ring |
| DDT ZINC01530011 |
 |
−57.30 | 5.0 | Trichloromethyl group |
| Malathion ZINC01530799 |
 |
−42.81 | 3.6 | -CH3 of dimethyl thiophosphate |