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. 2015 Nov 12;33(1):27–32. doi: 10.1007/s10815-015-0611-2

Table 1.

Reports of high order (≥3) monochorionic pregnancies following ART in the literature to date

Publication Zona pellucida breach Embryonic stage No of ET Pregnancies conceived Intervention Outcome
ICSI Assisted hatching Embryo biopsy
Salat-Baroux et al., 1994 No No No Cleavage 4 MCTA triplets Reduction DCDA miscarriage
DCDA twins
Belaisch-Allart et al., 1995 No No No Cleavage 3 MCTA triplets Nil Delivery ?weeks
Yakin et al., 2001 Yes No No Blastocyst 3 MCTA triplets Reduction DCDA delivery 36 weeks
DCDA twins
Ghulmiyyah et al., 2003 Yes Yes No Blastocyst 2 MCTA triplets Nil CS at week 31
Ulug et al., 2004 Yes Yes No Cleavage 3 MCTA triplets Reduction Singleton CS at week 38
Singleton
Yes Yes No Cleavage 3 MCTA triplets Nil CS at week 34
Unger et al., 2004 Yes No No Blastocyst 2 MCTA triplets Reduction Ongoing MCDA pregnancy 22 weeks
MCDA twins
Zikopoulos et al., 2004 Yes No No Blastocyst 2 MCTA triplets Reduction Ongoing MCDA pregnancy 20 weeks
MCDA twins
Risquez et al., 2004 Yes Yes No Cleavage 1 MCTA triplets Nil Ongoing pregnancy
16 weeks
Jain et al., 2004 No No No Blastocyst 2 MCTA triplets Nil Ongoing pregnancy 7 weeks
Henne et al., 2005 No No No Blastocyst 2 MCTA triplets Termination
Yanaihara et al., 2007 No No No Blastocyst 1 MCTA triplets Termination
Lee et al., 2008 Yes No No Blastocyst 1 MCTA triplets Nil CS at 33 weeks
Faraj et al., 2008 No No No Blastocyst 1 MCTA triplets Nil CS at 32 weeks
Pantos et al., 2004 Yes Yes No Day 4 3 MCTA triplets Reduction Singleton CS at 38 weeks
singleton
Haimov-Kochman et al., 2009 Yes No Yes Day 4 3 MCTA triplets Reduction Singleton delivery at 38 weeks
singleton
Liu et al., 2010 No No No Cleavage 2 MCQA Nil Miscarriage
Gurunath et al., 2015 No No No Blastocyst 2 MCTA Termination
Saravelos et al., 2015 Yes No Yes Day 4 1 MCQA Reduction MCDA CS at 35 + 6 weeks
No No No Blastocyst 1 MCTA Reduction Ongoing MCDA pregnancy

ET embryos transferred, CS caesarean section, DCDA dichorionic diamniotic, MCDA monochorionic diamniotic, MCTA monochorionic triamniotic