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. 2015 Apr 22;24(2):277–283. doi: 10.1038/ejhg.2015.85

Figure 2.

Figure 2

Multiple scatterplot of X12063 values vs age. Five black regression lines correspond to the X12063 average values in individuals carrying from 0 (the lower thin line) to 4 (upper heavy line) ‘+' alleles in rs4646450-rs4363657 genotype. The regression line corresponded to carries of two ‘+' alleles (double heterozygotes) overlay the population average (the middle line). Comparison of the genotype-specific regression lines gives statistically highly significant difference by LRT (P=2.3E−62) and the ‘+' allele explains 10.52% of the X12063 variation. The ‘+' allele for each of two SNPs is defined in Table 3.