Table 1.
Patient characteristics and DBS settings applied following 24 months of chronic ALIC-NA DBS.
# | Gender | Age at surgery | OCD symptoms | Response to DBS (YBOCS change) | DBS contacts and voltage | DBS frequency and pulse width | |
---|---|---|---|---|---|---|---|
Right side | Left side | ||||||
1 | F | 33 | Con Was Avo Anx | Best (68%) | 1− C+, 5.0 V | 0− C+, 5.0 V | 135 Hz, 210 μs |
2 | M | 52 | Dou Avo Che | No (−3%) | 1−2− C+, 4.0 V | 1−2− C+, 1.5 V | 135 Hz, 90 μs |
3 | M | 39 | Dou Che | Little (28%) | 0−1− C+, 8.0 V | 0−1− C+, 8.5 V | 135 Hz, 150 μs |
4 | M | 33 | Con* | No (5%) | 0−1−2− C+, 3.5 V | 0−1−2− C+, 3.0 V | 60 Hz, 180 μs |
5 | F | 33 | Con Avo Anx | Little (33%) | 0−1− C+, 3.0 V | 0−1− C+, 3.0 V | 135 Hz, 210 μs |
6 | F | 27 | Con Avo Anx Was Cou | Best (86%) | 1− 0+, 3.5 V | 1− 0+, 3.3 V | 135 Hz, 90 μs |
Response to DBS is shown as YBOCS improvement compared to pre-operative assessments. The contacts of the DBS electrode are labeled from 0 to 3 for both sides, where contact 0 is the most ventral contact. A negative value for patient 2 indicates impairment. A negative value for patient 2 indicates impairment. Patient 4 (*) also suffered from Tourette syndrome as comorbidity. The stimulation frequency of 60 Hz was applied after usage of 135 Hz for 1 year turned out not to be beneficial. Abbreviations: Anx, Anxiety; Avo, Avoiding; C, stimulator case; Che, Checking; Con, contamination obsessions; Cou, Counting; DBS, Deep Brain Stimulation; Dou, Doubts; Was, Washing; YBOCS, Yale-Brown Obsessive Compulsive Scale.