Table 4.

Poisson regression analysis of eGFR slope at −2.0 mL/min/1.73 m²/year for 18 participants who met the UCPR goal

Variable	Relative risk	95% CI	p Value
Age: ERT started (years)	1.072	1.008 to 1.139	0.026
Interval: ERT start to visit 0 (years)	0.881	0.771 to 1.006	0.062
Average systolic blood pressure (mm Hg)	1.011	0.991 to 1.033	0.287
Average UPCR during treatment (mg/g)	1.479	0.630 to 3.468	0.369
Male gender	1.130	0.637 to 2.005	0.675
Medication score	1.392	0.859 to 2.254	0.179

Relative risk presented as ratios (95% CI). Medication score defined as: 0, none; 1, ACE inhibitor or ARB; 2, ACE inhibitor plus ARB, or diuretic; 3, ACE inhibitor or ARB at maximum dose. p<0.05 for risk ratios from Poisson regression model (shown in bold).

ARB, angiotensin type 1 receptor blocker; eGFR, estimated glomerular filtration rate; ERT, enzyme replacement therapy; UPCR, urinary protein to creatinine ratio (g/g).