FIG. 3.

SUL, CMN, and QRN each inhibit DNA synthesis, while inducing G₂/M cell cycle arrest. Hepa1c1c7 cell cultures were treated with increasing concentrations of phytonutrients for 24 h, before measurement of [³H] thymidine incorporation (A) or analysis by flow cytometry (B). Mean values (±SEM) are expressed as the percentage of control [³H] thymidine incorporation (A, n = 5) and percentage of control cells within G₂/M cell cycle phases (B, n = 4). Asterisks (*) indicate significant differences (P < .05) compared to the respective control groups.