SUL, CMN, and QRN trigger mitotic catastrophe, at relatively low concentrations. Hepa1c1c7 cell cultures were treated with increasing concentrations of phytonutrients for 24 h, before Wright–Giemsa staining and examination under light microscopy. Concentrations as low as 1 μM SUL, 1 μM CMN, and 0.01 μM QRN produced aberrant mitotic figures (see arrows, B and F) and micronucleation (see arrow, D). The higher 10 μM RES concentration produced only apoptotic bodies (see arrows, H).