Table 3.
Factors Associated with Presence of Metabolic Syndromea
| Univariate analysis | Multivariate analysis | |||||
|---|---|---|---|---|---|---|
| Characteristic | Odds ratio | Confidence interval | p Value | Adjusted odds ratio | Confidence interval | p Value |
| Age | ||||||
| 20–25 | REF | REF | REF | REF | REF | REF |
| 26–40 | 1.32 | 0.48–3.62 | 0.58 | 1.54 | 0.56–4.31 | 0.40 |
| >40 | 2.44 | 0.54–7.09 | 0.10 | 3.22 | 1.06–9.82 | 0.04 |
| Sex, female | 1.56 | 0.91–2.66 | 0.10 | 1.81 | 1.02–3.23 | 0.04 |
| Duration on HAART | 2.08 | 0.58–7.43 | 0.30 | N/A | – | – |
| Nadir CD4 count, | 1.00 | 0.99–1.00 | 0.73 | N/A | – | – |
| Current CD4 count | 1.00 | 1.00–1.00 | 0.81 | |||
| ART regimen | ||||||
| TDF/3TC/EFV | REF | – | – | REF | – | – |
| AZT/3TC/NVP | 1.76 | 0.95–3.25 | 0.07 | 1.67 | 0.89–3.14 | 0.11 |
| AZT/3TC/EFV | 1.00 | 0.51–1.94 | 0.99 | 1.05 | 0.53–2.08 | 0.88 |
| TDF/3TC/NVP | 1.26 | 0.20–7.82 | 0.80 | 1.23 | 0.19–7.96 | 0.83 |
| Family history of diabetes or hypertension | 0.96 | 0.49–1.87 | 0.90 | N/A | ||
| Current or former smoker | 0.82 | 0.44–1.52 | 0.52 | N/A | ||
a
Metabolic syndrome was defined as having two or more of the following: a fasting glucose of >100 mg/dL, triglycerides >150 mg/dL, HDL-C <40 mg/dL; waist circumference >102 cm in men and >88 cm in women.17