Table 5.

Association between the presence of P. gingivalis or Lys-gingipain and the clinicopathologic features of ESCC patients

Factors	Pg positive cases (%)	KGP positive cases (%)
ESCC samples (n = 100)	61(61)**	66(66)**
Adjacent normal tissues (n = 100)	12(12)**	17(17)**
Normal esophageal mucosa (n = 30)	0(0)**	0(0)**
Gender
Male (n = 70)	45(64.3)	48(68.6)
Female (n = 30)	16(53.3)	18(60.0)
Age (years)
≤60 (n = 39)	24(61.5)	23(59.0)
>60 (n = 61)	37(60.7)	43(70.5)
Smoking history
Smoking (n = 45)	31(68.9)	32(71.1)
Non-smoking (n = 55)	30(54.5)	34(61.8)
Differentiation
Well (n = 22)	8(36.4)*	10(45.5)*
Moderate (n = 58)	35(60.3)*	39(67.2)*
Poor (n = 20)	18(90.0)*	17(85.0)*
Lymph node metastasis
Positive (n = 38)	32(84.2)*	31(81.6)*
Negative (n = 62)	29(46.8)*	35(56.5)*
TNM stage
I+ II (n = 68)	33(48.5)*	39(57.4)*
III (n = 32)	28(87.5)*	27 (84.4)*

“**”and “*”indicate p < 0.01 and p <0.05, respectively