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. 2016 Jan 19;9:24. doi: 10.1186/s13071-016-1292-0

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© Le Rutte et al. 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Predicted prevalence of infective sandflies during IRS. Pre-IRS prevalence levels of infective sandflies represent a setting with 10 annual VL cases per 10,000 capita. IRS is assumed to start in the year zero, and to be implemented optimally (63 % reduction in sandfly density). The three colored lines represent the sub-variant of each of the three models that best fit age-patterns in human infection markers. See Additional file 4 for low, medium and highly endemic settings with optimal and sub-optimal IRS