Table 3.
Parameter | P1000/Ca0 | P1000/Ca500 | P1000/Ca1000 |
---|---|---|---|
Plasma calcium [mmol/l] | |||
Placebo | 2.36±0.08 | 2.36ab±0.06 | 2.36±0.08 |
4 weeks | 2.34±0.07 | 2.35a±0.05 | 2.38±0.08 |
8 weeks | 2.37±0.09 | 2.39b±0.07 | 2.39±0.09 |
Fecal calcium [mg/g feces] | |||
Placebo | 9±5 | 7±3* | 8±3* |
8 weeks | 8±4 | 11±5 | 12±6 |
Plasma phosphate [mmol/l] | |||
Placebo | 1.20±0.23 | 1.28±0.16 | 1.19±0.23 |
4 weeks | 1.19±0.19 | 1.24±0.14 | 1.23±0.20 |
8 weeks | 1.18±0.23 | 1.20±0.12 | 1.23±0.19 |
Fecal phosphorus [mg/g feces] | |||
Placebo | 5±2* | 5±2* | 6±3* |
8 weeks | 8±4 | 8±4 | 8±3 |
Plasma magnesium [mmol/l] | |||
Placebo | 0.82±0.06 | 0.83±0.04 | 0.82±0.05 |
4 weeks | 0.82±0.05 | 0.83±0.04 | 0.82±0.05 |
8 weeks | 0.83±0.05 | 0.84±0.05 | 0.81±0.05 |
Urine magnesium [mg/d] | |||
Placebo | 113a±41 | 110±30 | 106±48 |
4 weeks | 89b±39 | 103±36 | 91±42 |
8 weeks | 84b±32 | 103±53 | 106±56 |
Fecal magnesium [mg/g feces] | |||
Placebo | 2±1 | 2±1 | 2±1 |
8 weeks | 2±1 | 2±1 | 2±1 |
n = 62 for plasma and minerals in urine; n = 61 for fecal minerals; data are expressed as mean ± standard deviation; P1000/Ca0: 1000 mg phosphorus/0 mg calcium; P1000/Ca500: 1000 mg phosphorus/500 mg calcium; P1000/Ca1000: 1000 mg phosphorus/1000 mg calcium; a b mean values within a column with dissimilar superscript lower case letters are significantly different (p ≤ 0.05); * significant different to eight weeks within each group (p ≤ 0.05); effect of time was tested using general linear model with repeated measurements (with pairwise comparisons based on Bonferroni); fecal minerals were tested with paired and with unpaired Students t-Test within each intervention group and between intervention groups, respectively.