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. 2016 Jan 19;13:5. doi: 10.1186/s12986-015-0059-5

Table 2.

Plasma amino acid concentrations in the obese, nonobese, visceral obese, and nonvisceral obese groups

Overall Obese Nonobese p valuesa Visceral obesity Nonvisceral obesity p b
(nmol/ml) (n = 83) (n = 10) (n = 73) (n = 18) (n = 75) valuesa
Essential AAs
 Histidine 85.42 ± 9.71 88.02 ± 9.95 85.06 ± 9.69 0.370 84.83 ± 7.94 85.58 ± 10.19 0.774
 Isoleucine 64.07 ± 12.09 72.94 ± 12.74 62.86 ± 11.57 0.013 70.99 ± 10.59 62.16 ± 11.85 0.005
 Leucine 125.07 ± 20.71 139.34 ± 15.73 123.12 ± 20.62 0.019 136.51 ± 15.93 121.90 ± 20.85 0.007
 Lysine 187.46 ± 26.41 208.75 ± 23.59 184.55 ± 25.56 0.006 186.83 ± 21.20 187.64 ± 27.82 0.909
 Methionine 26.51 ± 3.71 26.69 ± 3.89 26.48 ± 3.71 0.871 25.81 ± 3.97 26.70 ± 3.65 0.370
 Phenylalanine 57.67 ± 6.79 59.54 ± 4.86 57.41 ± 7.00 0.356 59.13 ± 8.34 57.26 ± 6.31 0.305
 Threonine 129.23 ± 26.66 126.43 ± 19.06 129.61 ± 27.62 0.726 122.77 ± 23.68 131.02 ± 27.33 0.248
 Tryptophan 56.04 ± 10.08 53.93 ± 6.27 56.33 ± 10.49 0.484 61.94 ± 15.43 54.40 ± 7.38 0.004
 Valine 231.17 ± 30.90 261.89 ± 27.62 226.96 ± 29.03 <0.001 244.87 ± 25.78 227.38 ± 31.30 0.033
Nonessential AAs
 Alanine 342.61 ± 79.73 359.03 ± 99.02 340.36 ± 77.28 0.491 349.52 ± 83.12 340.70 ± 79.33 0.681
 Arginine 66.10 ± 16.33 70.04 ± 17.12 65.56 ± 16.27 0.420 64.26 ± 10.86 66.62 ± 17.58 0.591
 Asparagine 46.49 ± 6.19 46.17 ± 7.03 46.53 ± 6.12 0.865 42.73 ± 5.92 47.53 ± 5.89 0.003
 α-ABA 20.11 ± 5.50 22.01 ± 5.98 19.85 ± 5.42 0.247 20.17 ± 6.39 20.10 ± 5.28 0.963
 Citrulline 28.34 ± 6.20 26.23 ± 6.23 28.63 ± 6.19 0.254 25.57 ± 4.99 29.11 ± 6.32 0.031
 Cystine 36.67 ± 6.41 41.47 ± 7.06 36.02 ± 6.08 0.011 37.59 ± 7.53 36.42 ± 6.11 0.497
 Glutamate 57.93 ± 19.19 70.06 ± 17.04 56.27 ± 18.97 0.032 71.88 ± 24.25 54.07 ± 15.68 <0.001
 Glutamine 524.27 ± 55.46 514.17 ± 80.48 525.66 ± 51.75 0.542 495.84 ± 60.17 532.15 ± 51.86 0.013
 Glycine 220.56 ± 34.87 197.88 ± 41.43 223.67 ± 33.00 0.027 193.69 ± 30.16 228.00 ± 32.51 <0.001
 Ornithine 80.34 ± 16.80 86.87 ± 14.91 79.44 ± 16.94 0.192 81.85 ± 15.20 79.92 ± 17.30 0.669
 Proline 147.67 ± 39.39 141.67 ± 32.09 148.50 ± 40.40 0.610 151.29 ± 33.02 146.67 ± 41.15 0.662
 Serine 116.31 ± 19.30 112.34 ± 15.82 116.86 ± 19.76 0.491 104.54 ± 16.36 119.57 ± 18.87 0.003
 Taurine 74.99 ± 18.72 69.79 ± 15.03 75.70 ± 19.15 0.352 71.52 ± 15.75 75.95 ± 19.47 0.377
 Tyrosine 61.26 ± 9.71 66.44 ± 13.47 60.55 ± 8.97 0.072 62.76 ± 9.47 60.84 ± 9.80 0.461

Data are mean ± SD. obese: BMI ≥ 25, nonobese: BMI < 25; visceral obesity: visceral fat area ≥ 100 cm2, nonvisceral obesity: visceral fat area < 100 cm2

AA amino acid, α-ABA α-aminobutyric acid, BMI body mass index

aObese vs Nonobese, bVisceral obesity vs Nonvisceral obesity. Bold numbers indicate significant differences between the two groups with p <0.05